In our new article, we explore one important aspect of the evolution of big pharmaceutical companies towards new models of development : the outsourcing of their R&D capacities, evolving towards a Search & Development model. Is it now widely recognized that the big pharmaceutical companies have completely remodeled their R&D system for drug development. Continue reading
Essentials of the Week : January 9 – 20
Seems like nothing can stop the dynamic pace of innovation that is happening at the beginning of this year ! As usual we dig for the best and latest news, and the harvest is very prolific ! And NO we are not talking about Megaupload’s closure by FBI ! Enjoy these articles and don’t hesitate to share them !
Article of the Week :
2011 Venture Capital Report – A Record Year with $30.6 Billion Invested in 3051 Deals - CB Insights
Continue reading
The new translational research center of NIH: one step closer to opening !
Fait accompli! The National Center for Advancing Translational Sciences (NCATS) is launched by the NIH !The Obama administration will provide $30.7 billion to NIH for FY 2012 which includes $576.5 million to fund the NCATS. This article presents this new center that will focus on advancing translational research projects and moving basic research findings into applied innovations. A major step of the Obama Administration for innovation.
Innovation activities in the US: 2011 report, 2012 trends, a French perspective !
Jointly drawn up by David and Antoine, the paper explores the recent trends impacting US innovation activities in 2011. It also identifies the key questions facing the funding of innovation, including the VC activities in 2012 and the development of new funding schemes. A large section of the paper addresses the US Federal policy in the field of innovation, including the “Start up America” initiative. Although challenged by various negative factors, such as the poor economic outlook, the US innovation system appears both robust and flexible.
Read the full article (in French)
And that’s only the first part ! Next week’s article will explore the new funding and support methods for entrepreneurs, and will highlight the hottest US industries and clusters for 2012 !
Learning more about chromosome fragility

© Anne Helmrich
Why are some chromosomal regions particularly susceptible to breakage? Finding the answer to this question is crucial because this fragility is a factor in tumour development. A team from the Institute of Genetics and Molecular & Cellular Biology (CNRS/Inserm/University of Strasbourg) has just solved part of the mystery. Laszlo Tora and his colleagues have discovered that breakage in the longest human genes is caused by a phenomenon that, until now, was thought unlikely to occur in mammalian cells: interference between two key genetic processes, DNA transcription[1] and replication[2]. This research, published in the journalMolecular Cell on 23 December 2011, could eventually lead to novel strategies for fighting tumours.
Continue reading
Record Breaking Explanets Discovered !

Copyright S. Charpinet
An international team led by a CNRS researcher from the Institut de Recherche en Astrophysique et Planétologie (IRAP, CNRS – Université Toulouse III – Paul Sabatier) has discovered the ruins of a planetary system, consisting of the cores of two former giant planets stripped of their gaseous envelopes, orbiting around the remnants of the core of a red giant. These two exoplanets are the smallest, hottest and closest to their parent star ever discovered. This finding, published in the 22 December 2011 issue of the journal Nature. could shed new light on the fate of planetary systems.
From Basic Research to the Creation of Gatorade: The Challenges of Technology Transfer in the Amercian universities
“On September 16, 2011, President Obama announced the signature of the America Invents Act that that will help American entrepreneurs and businesses bring their inventions to market sooner, creating new businesses and new jobs. He also announced new steps that will help America’s universities and research labs convert ideas into new products, create startups, expand the economy and create high-value 21st century jobs.
Following this memoranda, the Association of Public and Land-grant Universities (APLU) has set up webinar series where vice-presidents of research in each university highlights specific plans for enhancing technology transfer activities in response to President’s call for action
Practices related to technology transfer are very different in universities. Each university has its own experiences and organizations in this field.
The U.S. Research Federal Budget for 2012 : Which Importance for Innovation ?
Summary This paper also elaborates on the U.S. industry R&D in 2012, which is expected to increase by 3.8%, reaching $ 250 Bi. A larger part of this R&D increase relates to offshore innovation of the U.S. industry.
Essentials of the week : January 2-9
welcome back for this new edition of the Essentials of the Week, the first of 2012 ! The year is off to a flying start with great news and forecast for the weeks and months to come. No doubt that Innovation & Entrepreneurship will be the flagship of the year, and the key to growth & definite recovery. Take a look at our selection !
Article of the Week
Is Massachusetts Losing its Edge ? - John Towne – Business Telegram
Innovation
5 Steps to Increase Innovation Skills Set - Innovation Management – Marc Juszczak
Tony Fadell’s Newest Invention is the iPod of Thermostats – Fast Company – John Pavlus
Continue reading
The Most Innovative Countries in the World : France Rises to 3rd Place !
Every country wants to win this new title : the most innovative country in the world. Ask anyone about this, and the answer will almost always be the same : the United States of America. And they’re right, the USA are the biggest innovation generator in the world, thanks to a broad range of universities and companies that keep inventing the next generation products and technologies.
But who’s next ? Thomson Reuters gives you the answer in this beautiful infographic below. And Cocorico, France is ranked 3rd, with an excellent result ! So take a look at this chart and see how your country is doing !
